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How much clozapine can I take? Clozapine is usually taken 1 or 2 times per day with or without food. Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks. The dose usually ranges from 25 mg to 700 mg. Only your healthcare provider can determine the correct dose for you.
Why is clozapine so effective? Why clozapine is more effective for treatment-resistant schizophrenia than other antipsychotic agents remains uncertain. Most patients respond to dopamine blockers, but clozapine probably does something on top because it helps those patients who don't respond to other agents," points out Dr Gaughran.
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