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I have been on Gleevec now for 6 months and in that time I have had maybe 5 well days, the other days have been filled with vomiting, nausea, body aches & pains, migraines, lethargy, insane amounts of facial swelling and my weight is just up & down like a yoyo, varying from 82kilos down to 75. I now realize that when I said this wasn't the right medication for me 5 months ago I was right. Today my hematologist told me that my Philadelphia gene is unacceptably high, so now I am going to try something else. I am delighted to hear that others are doing so well on it but it certainly wasn't for me

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After being diagnosed with CML about 4 years ago. I began taking Gleevec 400 daily. First couple months were most difficult. I personally was nauseous and had diarrhea. Things seemed to settle down. I now have swelling in the face, especially in the eye area, in turn creates migraines which now are controlled by medicines. I also still have the occasional diarrhea bouts. I am thankful for Gleevec as my BCR able has been less than 01% pretty much Full Remission.

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The annual rates of any progression events have decreased with time on therapy.

This list is provided to inform users of important studies that have helped shape the current understanding of and treatment options for CML.

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Showing Z9000 results grouped by tumor mutation status, Dr.

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Additionally, one might consider patient age, mutation status, current quality of life, other diseases, quality and quantity of tissue used to measure mitotic rate, and surgical findings (whether it was multifocal, whether there was possible tumor rupture), or positive margins).

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There were 456 (82%) patients on first-line imatinib who had achieved CCyR at any time during the study (two additional patients since the last update).

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The frequency of grade 3 and 4 toxicities that occurred during therapy was similar between the randomized groups, and there was no difference in cumulative incidence of second malignant neoplasms.

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