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Seizure has been estimated to occur in association with clozapine use at a cumulative incidence at 1 year of approximately 5%, based on the occurrence of 1 or more seizures in 61 of 1743 patients exposed to clozapine during its clinical testing prior to domestic marketing (i.

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Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study".

What is the most important information I should know about clozapine (Fazaclo)?

Treatment patterns suggest that local practice preferences are important in determining whether clozapine is prescribed ().

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LOCF for patients completing at least two weeks.

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Learned helplessness An understanding that one cannot control one's environment based on experience that efforts to exert control are ineffective.

Members of an ACT team are multidisciplinary and provide service ranging from medication management to rehabilitation support.

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In the clozapine screening guidelines, white blood cell count is mandatory.

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Through this criterion, and medium term studies indicated that 82% of the people taking clozapine and 81% on olanzapine did not improve.

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Universal safety standards Standards of behavior regarding safety that apply to everyone, such as requiring all passengers in a car to wear a safety belt.

The risk is greatest during the first month of clozapine therapy.

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Providing safety, structure, and support are immediate priorities in the therapeutic milieu for clients with cognitive impairment and inability to handle stress.

After a period of six months, the authors found that despite the costs of blood tests, the total cost of treatment with clozapine came down by nearly 25%.

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Elias TJ, Bannister KM, Clarkson AR, Faull D, Faull RJ: Clozapine-induced acute interstitial nephritis.

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